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Anabolic steroids are a class of drugs with a basic steroid ring structure that produces anabolic and androgenic effects. Common types include prednisolone and hydrocortisone creams, as well as methylprednisolone tablets and tablets. Methylprednisolone has been the most widely used prednisolone, with more than 60% of total prescriptions in the United States, according to the 2014 National Survey on Drug Use and Health (NSDUH). Although the long-term risks of steroids include potential death, serious injuries to the digestive system, damage to eyesight, liver damage, kidney problems and other serious health effects, no serious long-term effects have been reported on humans. How Are Prednisolone and Hydrocortisone Treated Prednisolone is most commonly taken orally through a transdermal (under the skin) patch. When needed, a gel-style patch is also used, but is considered to be more convenient. Oral prednisolone is also effective when given intravenously. Hydrocortisone creams are prescribed for short-term use to manage menstrual irregularities and postpartum pain. This form of treatment is used to treat vaginal irritation and infections caused by excessive menstrual bleeding. Prednisolone Depot and Tablet Replacement The steroid is replaced through an injectable form called the prednisolone dehydrogenase (PDH) inhibitor. This treatment usually takes four to five weeks to take effect. Dosing and Administration Injectable prednisolone treatment generally begins between two and four weeks after the last dose of oral prednisolone. However, the doses for short-term oral use, if needed, may occur as early as 48 to 72 hours following the last dose of oral prednisolone. Adults with type 1 diabetes may receive prednisolone injections for up to five months. Children and adolescents with type 1 diabetes will typically receive a treatment period of about two to 10 weeks, depending on the age of their diabetes and whether or not they start prednisolone for the first time. Prednisolone also has been found to be effective in preventing hypoglycemia in children with type 1 diabetes for up to six months after the last injection. There are additional treatment options available for people taking prednisolone for the first time. If you have questions or concerns related to the use of a medication, it is important to determine which option is best for you and your family. For more information on Similar articles: